Exercise Attenuates Ischemia-reperfusion Injury of Nonalcoholic Fatty Liver in OLETF Rat

been proposed to minimize the disadvantage of steatotic livers. These strategies may comprise donor weight loss through exercise, diet and modified food, employing drug therapy, heat shock preconditioning, ischemia preconditioning, selective anesthesia on donors and the treatment on isolated grafts during preservation [8]. In this respect, exercise training and increasing physical activity have been shown to attenuate fatty liver of animal models [9, 10]. Furthermore, physical exercise combined with an anti-hyperlipidaemia drug successfully reduced macrosteatosis of obese human living donors [11].